Brain Disease

Disorders affecting the brain are among the most costly to society because they can last for years to a lifetime. Work has focused on autism and Alzheimer disease and the potential role of environmental agents in causing these conditions.

Selected papers

Nataf, R., Skorupka, C., Amet, L., Springbett, A. and Lathe, R. (2006) Porphyrinuria in autistic disorder; implications for environmental toxicity. Toxicol. App. Pharmacol. 214, 99-108.

Lathe, R. (2006) Autism, Brain and Environment. Jessica Kingsley Publishers, London and Philadelphia

Lathe, R. (2009) Fragile X and autism. Autism 13, 194-197

Lathe, R. and Harris, A. (2009) Differential display detects host nucleic acid motifs altered in scrapie-infected brain. J Mol Biol. 392, 813-822

Lathe, R., Sapronova, A. and Kotelevtsev, Y. (2015) Atherosclerosis and Alzheimer – diseases with a common cause? Inflammation, oxysterols, vasculature. BMC Geriatr. 14, 36

Itzhaki, R.F., Lathe, R., Balin, B.J., Ball, M.J., Bearer, E.L., Braak, H., Bullido, M.J., Carter, C., Clerici, M., Cosby, S.L., Del Tredici, K., Field, H., Fulop, T., Grassi, C., Griffin, W.S., Haas, J., Hudson, A.P., Kamer, A.R., Kell, D.B., Licastro, F., Letenneur, L., Lövheim, H., Mancuso, R., Miklossy, J., Otth, C., Palamara, A.T., Perry, G., Preston, C., Pretorius, E., Strandberg, T., Tabet, N., Taylor-Robinson, S.D. and Whittum-Hudson, J.A. (2016) Microbes and Alzheimer’s Disease. J Alzheimers Dis. 51, 979-984

Lathe, R. and Haas, J.G. (2017) Distribution of cellular HSV-1 receptor expression in human brain. J. Neurovirol. Epub ahead of print